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The unprecedented demand for GLP-1 receptor agonists is driving pharmaceutical companies to invest heavily in peptide API production, fill-finish facilities, and injectable manufacturing capacity

Although some studies have shown an increased risk for thyroid cancer and pancreatitis in human patients, these studies are difficult to interpret due to reporting bias, lack of controlling for other patient medical histories and comorbidities, the fact that obese people are already highly at risk for specific forms of cancer and may already have primordial tumours present when beginning medication and are likely to be taking other medication apart from GLP1R agonists as well [55]

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