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The mechanism behind this effect is not yet fully understood
The molecule itself was never the problem
Now, it is also clear that, not only testicular somatic cells (Leydig and Sertoli cells), but also germ cells express P450arom mRNA, which is translated in a biologically active enzyme involved in the production of estrogens
Gastrointestinal Disorders In very rare instances, severe inflammation of the stomach lining (gastritis) or the intestines could lead to bleeding
The pharmaceutical composition of claim 1, wherein said pharmaceutical composition is a liquid solution comprising an aqueous mixture of semaglutide, or a pharmaceutically acceptable salt, a permeation enhancer, a bioadhesive agent, a solubilising agent, a buffering agent, a chelator, a tonicity agent, and a preservative