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Serum trimethylamine-N-oxide is elevated in CKD and correlates with coronary atherosclerosis burden
Our experience shows that the most groundbreaking discoveries often come from this kind of comparative analysis
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Carnitine Carnitine is a quaternary ammonium compound involved in metabolism in most mammals, plants, and some bacteria
Other possible mechanisms to improve insulin sensitivity in NAFLD reported in the literature include the regulation of the acetyl-CoA/CoA ratio in mitochondria, modulation of the pyruvate dehydrogenase complex (PDHC) activity, altering the expression of glycolytic and gluconeogenic enzymes as well as the expression of genes associated with the insulin signaling cascade, and stimulation of the insulin-like growth factor-1 (IGF-1) axis and IGF-1 signaling cascade (57)
Apr 2021;27(1):8-14
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