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Samples were reduced with dithiothreitol at 10 mM for 30 minutes at 56C and alkylated with iodoacetamide at 30 mM for 45 minutes at room temperature in the dark

Imiquimod is a strong inhibitor of tumor cell-induced angiogenesis

They offer significant benefits in terms of weight loss and blood sugar control, which can help reduce many obesity-related health complications

Due to both this potential interaction and topiramate's teratogenic risk, highly effective contraception is required for women of childbearing potential taking topiramate