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Even though the BBBs function is slightly compromised at this stage, it does not significantly hinder the delivery of NPs

Third-Party Tested: Independent verification of purity and composition

Then, the WEN participated in the application of a control (n = 35) and high antioxidant diet (n = 37) for four months

26 , 420432.e429 (2019)

In addition, glutathione (GSH) and N-acetylcysteine (NAC) restore intracellular redox equilibrium by replenishing GSH pools and activating AMPKNrf2HO-1 signaling, which promotes ROS detoxification and suppresses apoptotic cascades (89)

Groups were assigned as MTX-vehicle, NTZ-100, and NTZ-200 groups (at 100 and 200 mg/kg/day, gavage, respectively), N-acetyl cysteine (NAC) group (500 mg/kg), and 4-phenyl butyric acid (4-PBA) group (150 mg/kg, i.p)