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73 A earlier meta-analysis of data from 17 randomized placebo-controlled trials with a total of 284 participants found melatonin supplementation improved sleep parameters, but the effects were small: in a subset of 15 trials in individuals who were either healthy or had insomnia but were otherwise healthy, the time needed to fall asleep decreased by 3.9 minutes, sleep efficiency improved by 3.1%, and total sleep time increased 13.7 minutes

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Regular follow-up appointments should include assessment of patient response, monitoring for adverse effects, and evaluation of the need for dose adjustments

Semaglutide is a medication designed to help manage blood sugar levels in people with type 2 diabetes and aid in weight loss for those who are overweight or obese

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