Further research is needed to confirm causality, identify high risk groups, and guide monitoring strategies
Cost and device differences affect adherence and continuity, with reported out-of-pocket costs ranging from $99 per month for compounded prescriptions to nearly $1,000 per month for some branded pens without insurance, and device switches often trigger missed titration steps
These drugs may also change how the brain responds to sweet tastes
Regular exercise also strengthens the heart, supports metabolism, and helps the body adjust naturally to weight changes
Due to the rapid reduction in facial volume, semaglutide may also accelerate the aging process, altering the size, shape, and proportion of features such as the lips, chin, and cheeks
Most patients begin noticing weight loss within 4-8 weeks of starting semaglutide, with continued fat reduction over 12-18 months as the dose is gradually increased