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20-100 M
To enhance its bioavailability, drug delivery systems including emulsions, nanostructured lipids, hydrogels, and liposomes have been recommended and employed with some success including improved chemical stability, better penetrability, and enhanced bioactivity [144, 153,154,155,156]
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The current study did not find an APOE genotype effect on the cerebrovascular uptake of L-carnitine, its metabolites, or FAs at 26 weeks of age