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This is exactly the kind of question that requires large, long-term pharmacovigilance data
The New England Journal of Medicine , 384(11), 9891002
PMCID: PMC12643026
Both Vitamin D2 and D3 are available as supplementsD3 is produced on the surface of the skin in response to ultraviolet light, or from egg yolk or fatty fish (supplementation with D3 oil in doses from 1000 IU may be beneficialhigher doses can lead to nausea, vomiting, frequent urination, and kidney stones)
37 Increased GLUT1 in HSCs can also be induced by TGF-1 through the Smad, p38 MAPK, and PI3K/AKT pathways
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