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Absolute concentration should therefore be interpreted alongside GSSG, total pool size, sample viability, and pathway context

Additionally, in Mecp2 KO mice, GABA transporter GAT3 expression is increased in the hippocampus, along with corresponding increases in GAT3 currents in hippocampal astrocytes, and long-term administration of GAT3 antagonists can improve symptoms in Mecp2 KO mice (78)

If you take them with a meal, the chances of the molecule being broken down and wasted are much higher

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