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The carnitine bound OCTN2-occluded structure defines the substrate and sodium ion binding sites In the presence of 10 mM l-carnitine the structure of OCTN2 was determined in the fully occluded, carnitine- and Na + -bound conformation (Fig

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Our previous data indicated that the above behavioral deficits evoked by repeated treatment with BSO alone and in combination with GBR 12909 were also reversed by repeated treatment with a higher dose of aripiprazole and by co-treatment with ineffective doses of aripiprazole and escitalopram (38)