Peer review Peer review information Nature Communications thanks Reza Vafabakhsh, Sudarshan Rajagopal and the anonymous reviewer(s) for their contribution to the peer review of this work
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Clinical trial data from the SURPASS program, which evaluated tirzepatide across various doses and patient populations, demonstrated that hypoglycemia rates with tirzepatide monotherapy were generally low
GLP-1 users with type 2 diabetes and stage 3 kidney disease had substantially lower mortality and lower rates of several malignancies, particularly lung, colorectal, and hepatocellular cancers, than non-users