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This is more common during the first few days of taking the supplement
The hypothetical estimand (on-treatment without rescue medication) showed a statistically significant difference between the 16 mg and 2 mg groups, for both the HbA1c reduction and a weight loss with -0.5 percentage points (95 % CI: -1.0 to -0.1
In 2022, the FDA expanded that indication to include children aged 12 years and older with obesity
doi: 10.1016/j.cell.2012.03.042 CrossRef Google Scholar View reference in article 5 MaHWangXZhangWLiHZhaoWSunJet al
Mechanistic basis is plausible
Turksen, K.) 763, 369382 (Humana Press, 2011)
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/profile/Asfandyar-Sheikh/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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