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17 Rosenstock, J., et al., Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): a double-blind, randomised, phase 3 trial

Limitations: Primarily used to treat diabetes

A Novo Nordisk spokesperson responded to the study in July, saying that NAION isnt an adverse drug reaction for the marketed formulations of semaglutide and taking issue with what they called key methodological limitations to the study

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J Clin Med 11(13):3649 Tanase DM, Gosav EM, Costea CF, Ciocoiu M, Lacatusu CM, Maranduca MA, Ouatu A, Floria M (2020) The intricate relationship between type 2 diabetes mellitus (T2DM), insulin resistance (IR), and nonalcoholic fatty liver disease (NAFLD)

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