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Before Your Treatment Comprehensive labs including fasting glucose, HbA1c, lipids, metabolic panel, and thyroid are drawn before initiating Bring a complete list of current medications GLP-1 agents interact with several drug classes Disclose personal and family medical history in detail Begin keeping a food/activity journal your provider will use this to personalize your protocol After Your Treatment Start with the lowest dose and titrate slowly to minimize GI side effects (nausea, constipation) Stay well hydrated GLP-1 medications reduce the sensation of thirst Eat small, balanced meals avoid high-fat, high-sugar foods that worsen nausea Take protein intake seriously protect muscle mass during caloric restriction Monthly check-ins and labs are standard

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The transition from episodic to chronic migraine involves changes in nociceptive thresholds and central sensitization, driven by factors such as high frequency of migraine attacks, overuse of acute medications, obesity, stress, female sex, psychiatric conditions, and low socioeconomic status (34)

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