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Behav Brain Res (2017) 316:110

You will feel the benefits of the B-12 injection within 48 to 72 hours of receiving the shot.

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Most clinicians prefer waiting eight to twelve weeks

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Most lipo C injection site reactions resolve within 2472 hours following a predictable pattern: redness peaks at 24 hours and fades by 1224 hours, swelling peaks at 46 hours and resolves by 4872 hours, and tenderness persists up to 72 hours but should not worsen after the first 12 hours