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One thing to consider is that because ME/CFS is a severely disabling disease, many patients are house or bedbound and are unable to visit the clinics multiple times for follow-up analyses (39), even though these very severe cases are estimated to be around 25% of the ME/CFS cases (39, 587)

Injection-site reactions are among the most commonly reported side effects: patients may experience pain, stinging, or mild burning at the IM injection site

Biology, 10 (6), 456

Patients receive detailed written instructions specific to their prescribed vial concentration and dose

Joosten LPT, van Doorn S, van de Ven PM, et al

doi:10.1111/bjh.12959