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The handful of studies examining body composition showed promise, but sample sizes were small and duration limited

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Conversely, restoration of NAD + levels reactivated PGC-1 signaling and mitigated alcoholic fatty liver disease

Others, including most of those under FDA review in July, are unapproved compounds that have nonetheless amassed a cult following among so-called looksmaxxers, bodybuilders, wellness influencers, and Silicon Valley biohackers