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GSH is synthesized by the consecutive action of two enzymes, glutamate-cysteine ligase and glutathione synthetase

The alterations were associated with indicators of heightened oxidative stress, including elevated malondialdehyde (MDA) levels and diminished antioxidant defences such as glutathione (GSH), superoxide dismutase (SOD), and catalase (CAT)

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Figure 1 Activation of PKA by cAMP results in release of its two catalytic subunits from the two anchoring regulatory subunits from specific cellular locations and anchoring proteins

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