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With mutagenesis studies, we propose an acyl-modification driven ghrelin-binding model, in which the binding of octanoyl group in cavity II orients the N-terminus of ghrelin to cavity I, and leads to the initiation of signal transduction

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10.3390/antiox11010170 101 TamagnoE.GuglielmottoM.VasciaveoV.TabatonM

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Methodologies varied: one randomized controlled trial in overweight and obese adults (n=32

Managing several vials in various stages of use without aliquoting creates chaos