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In DAPA-HF, at baseline, 94% of patients were treated with ACEi, ARB or angiotensin receptor-neprilysin inhibitor (ARNI, including sacubitril/valsartan 11%), 96% with beta-blocker, 71% with mineralocorticoid receptor antagonist (MRA), 93% with diuretic, and 26% had an implantable device (with defibrillator function)

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Common treatment areas include the under chin (double chin), jawline, abdomen, flanks, thighs, arms, and other localized zones

Always talk with a licensed healthcare provider before starting, changing, or stopping any medication or therapy

10.1089/dia.2011.0050 [DOI] [PMC free article] [PubMed] [Google Scholar] 48.Tomkin GH