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That matches what we know clinically: pharmacotherapy works best inside structured behavioural support, not instead of it or pitched against it

These symptoms usually fade on their own within a few hours or, at most, a couple of days

Several peripheral and central mechanisms are believed to be involved, including altered gut hormone secretion, decrease in energy expenditure following weight loss, and psychological processes associated with the food reward system

That brain involvement is central to understanding their mental health effects

In contrast, the placebo (inactive treatment) group lost about 6 pounds on average, or about 2% of their body weight

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