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For individuals seeking visible skin benefits or long-term antioxidant support, this format offers a more reliable and bioavailable approach (NIH)

Studies have shown that vitamin D inhibits the activation of the TGF- 1/Smad3 signaling cascade by blocking Smad3 phosphorylation

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The histone methyltransferase NSD1 has been identified as having potential therapeutic value by upregulating the H3K36me2 modification, thereby activating the expression of the transcription factor SOX9, which subsequently downregulates the key enzyme for ferroptosis, ACSL4, thus attenuating chondrocyte ferroptosis (170)