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[1] [2] This occurs because B12 deficiency commonly affects the peripheral nerves, particularly those extending to the extremities

Gut 2003;52:6570

Alternative diagnoses and diagnostic categories include, but are not limited to: Neuromuscular disorders (such as myopathic EDS and Bethlem myopathy) Other heritable connective tissue disorders (such as other types of EDS, LoeysDietz syndrome, Marfan syndrome) Skeletal dysplasias (such as osteogenesis imperfecta) HSD in Adults Adults are diagnosed with HSD if they have symptomatic joint hypermobility that cannot be explained by other conditions

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