The most common reasons: using a standard (non-effervescent, non-liposomal) capsule with poor gut absorption, inconsistent daily use, expecting visible results before the typical 8-12 week window, unrealistic expectations set by marketing claims, low supporting nutrients like Vitamin C, or continued sun exposure without adequate sunscreen, which counteracts skin brightening effects
Upon conjugation of bis DOCA or tetra DOCA to the GLP-1A peptide, their P app values were further reduced by 1.42-fold and 1.52-fold, respectively, compared with m D-G1A after Act D treatment
lower complication rate Roux-en-Y gastric bypass (43644): ~3035% EBWL
Saxenda may require long-term use
Drugs 1982
doi: 10.1007/s11154-023-09825-1 13 MullerTDFinanBBloomSRD'AlessioDDruckerDJFlattPRet al