Secondary SID may improve or resolve when the underlying condition is treated.18 Theres an increased prevalence of sucrase-isomaltase gene variants in patients with IBS, suggesting that SID may be misdiagnosed as IBS in some cases.19 Sucraid (sacrosidase) is an FDA-approved prescription enzyme for the treatment of genetically determined sucrase deficiency.21 In a randomized, double-blinded trial, 81% of congenital SID patients were asymptomatic on an unrestricted diet with the use of sacrosidase.22 Because sacrosidase provides enzyme replacement for sucrase but not for isomaltase, some patients on sacrosidase may need to limit starch intake for further symptom management.21 The recommended dose for sacrosidase is 1 mL (8,500 IU) in patients weighing 15 kg or less and 2 mL (17,000 IU) in patients weighing more than 15 kg
DHARMA beat
Several companies are working on a device called a continuous ketone monitor (CKM) or dual CGM-CKM, which combines ketone monitoring and glucose monitoring in one sensor
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