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Description

Mechanical manipulation of cancer cell tumorigenicity via heat shock protein signaling

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Hirabayashi, T

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A.et al (2022)

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Niacinamide is a form of Vitamin B3

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They revealed that BHD diminishes lactylation modifications, including Pan-Kla and H3K18la, by restricting lactate synthesis, which leads to the normalization of apoptotic protease activating factor-1 (Apaf-1) transcription levels and ultimately promotes cellular survival [126]

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