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doi: 10.1152/ajpregu.00011.2020
Castellsague J, Gel B, Fernandez-Rodriguez J, Llatjos R, Blanco I, Benavente Y, et al
Gamma-glutamyltransferase is associated with incident vascular events independently of alcohol intake: analysis of the British Womens Heart and Health Study and Meta-Analysis [published correction appears in Arterioscler Thromb Vasc Biol
It will be important to consider the specific GLP1-RAs that have shown clear benefit in the reduction of MI risk when integrating them into contemporary primary and secondary ASCVD prevention guidelines
STEP 1 (Wilding et al., 2021, New England Journal of Medicine) enrolled 1,961 participants and demonstrated a mean body weight reduction of 14.9% at 68 weeks with 2.4mg subcutaneous semaglutide, the first pharmacological intervention to produce weight loss of this magnitude in a Phase 3 trial, establishing a new efficacy benchmark that became the comparison standard for all subsequent metabolic compounds including Tirzepatide and Retatrutide
Open Sleep J
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