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In mice in which the GLP-1R gene has been knocked out the anorectic responses to injected OXM are abolished

When irradiated with light of a suitable wavelength, bilirubin can also occur in photoisomerization (through intramolecular hydrogen bonds breaking) and be converted to the more water-soluble photoisomer, which is readily disposed of and eliminated by the liver and kidneys (226, 235)

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