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Study on plasma metabolomics profiling of depression in Chinese community-dwelling older adults based on untargeted LC/GC-MS

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Retatrutide is an investigational drug and is not FDA-approved as of April 2026

A 2020 review in Diabetes Care noted that "the hypoglycaemic effect of IGF-1 has been exploited therapeutically in rare forms of insulin-receptor-defect syndromes, but the risk-benefit calculation differs fundamentally from use in euglycaemic individuals" [20]