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The clinical evidence for some of these agents (like SGLT2 inhibitors and statins) in improving cardiovascular outcomes is strong, supporting the concept that modulating pathways intertwined with oxidative stress is a viable therapeutic approach

Moreover, tumours did not show signs of oxidative stress or compensatory metabolic changes, such as accumulation of cysteine (Extended Data Fig

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Evidence level Mouse and cell studies only

Shared immune pathways: Eczema involves immune imbalance, typically a Th2skewed response with contributions from Th17 in some cases