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Consider initial therapy at this stage when glycated hemoglobin (HbA1C) 9% ( 75 mmol/mol)

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[253] reported changes in 30 microbial markers after quetiapine treatment, and 10 of them presented an area under the curve (AUC) of 0.93 between responder and no responder patients, denoting a potential application of gut microbiota as a predictive biomarker

In patients taking JANUMET XR whose eGFR later falls below 45 mL/min/1.73 m2, assess the benefit and risk of continuing therapy

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