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& Kahane, I.) 2952 (Springer US, Boston, MA, 1993)

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28-30 However, an unblinded randomized controlled trial (RCT) comparing the efficacy of metformin (500 mg 3 times daily) with rosiglitazone (4 mg/d), another T2DM medication, on AN neck lesions in patients who were overweight and obese found no significant effects in lesion severity and only modest improvements in skin texture in both groups at 12 weeks following treatment initiation

Creatinine, alanine aminotransferase, and electrolyte were measured by an auto-biochemical analyzer (Roche Diagnostics Corporation)

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