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E.MottramD.AlexandreE.RichertL.et al (2015)

GSH is also regenerated from GSSG by glutathione reductase (GR) in a NADPH-dependent reaction maintaining the intracellular GSH pool under sustained oxidative challenge

As the active, reduced form of glutathione, it is highly effective in neutralizing free radicals, which are unstable molecules that cause oxidative stress and damage to cells

[29] Treating rodenticide poisoning [edit] Coumarin is used in the pharmaceutical industry as a precursor reagent in the synthesis of a number of synthetic anticoagulant pharmaceuticals

In this sense, it is evident that strategies aimed at restoring GSH levels could represent a new therapeutic option to prevent or alleviate the progression of diseases caused by oxidative stress

The Antioxidant Powerhouse Understanding Oxidative Stress and Its Impact on Health : Before diving deeper into glutathione's role, let's understand the concept of oxidative stress