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In the DUAL V, 40% of patients assuming Liraglutide/Degludec received 50 dose steps after 26 weeks corresponding to 1.8 mg of Liraglutide, with a wide range of variability also depending on baseline BMI (65)

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Thus, ADOR provides a potential target for treatment of PD and ADOR A2B agonists might be effective for PD in active stage

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