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Grade 0: Normal cartilage, no defects evident Grade 1: Superficial cartilage lesions: softening and/or superficial fissures/tears Grade 2: Lesions extending to 50% of the cartilage depth Grade 4: Entire cartilage layer missing, subchondral bone is exposed Which treatment technique

Short-term storage considerations include: Protecting vials from moisture Avoiding repeated temperature fluctuations Minimizing unnecessary light exposure Maintaining original packaging until use For extended storage periods, freezer conditions are generally recommended

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Tuntipopipat S, Zeder C, Siriprapa P, Charoenkiatkul S