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Biological sex: Women reach higher peak BAC than men from equivalent intake due to lower gastric ADH activity, lower body water percentage, and hormonal effects on ethanol absorption through the gastrointestinal tract

Kadakol et al

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Combining the results of several thousand such HIP HOP screens revealed that the cellular response to small molecules is limited and can be described by 45 signature chemical-genetic interaction profiles that are detectable in other large-scale genomic datasets, suggesting that they represent fundamental, conserved small-molecule response systems present across eukaryotic cells [10]

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