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Retrieved 4 March 2009

CANVAS Program Collaborative Group

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The thigh is one of the three recommended injection sitesalong with the abdomen and upper armbecause it offers good accessibility and a thick layer of subcutaneous tissue that absorbs medication reliably

Another second-line pharmacologic option is prucalopride, a 5-HT4 serotoninergic agonist, with an established dose applied orally every 24 hours.94,97 Prucalopride is a good option in patients that experience adverse effects related to GLP-1 agonists because it increases gastric emptying, augmenting rectal sensitivity and intestinal transit