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Serious adverse effects have not been widely reported, but long-term safety data in humans is lacking

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[1] [2] The severity of symptoms depends on several factors: the specific dose taken, individual patient tolerance, concurrent medications, renal function, and timing since the last meal

Until then, the notification said GLP-1 RAs should only be prescribed for their licensed indication, and clinicians should avoid initiating people with T2DM on GLP-1 RAs for the duration of the national shortage

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Similar lawsuits have been filed in the U.S