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Acknowledgements The authors want to thank the patient and her family for their generous participation in the dissemination of the insights gained from her care

In absence of A, mimicking the frail environment, CHGA added to neuronal-microglial co-cultures induces microglial toxin release, provoking neuronal inflammation and apoptosis 77

74 However, because these results were never formally published in peer-reviewed journals, they have to be taken with caution

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