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Tirzepatide is contraindicated in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2, prior serious hypersensitivity to tirzepatide, active or severe pancreatitis history, severe gastroparesis, and during pregnancy or breastfeeding

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However, when the FDA declared the semaglutide shortage resolved, the legal basis for most compounding operations changed significantly