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The loose stools people experience during calorie restriction are almost always linked to changes in the types of food eaten, the speed of dietary change, or medicines used alongside the diet not to the calorie reduction itself

But the margin for error shrinks dramatically

It is not about caloric or nutrient restrictions

Protection of retinal function by sulforaphane following retinal ischemic injury

Studying the mechanism of benefit in this group of subjects to seek the precision of treatment should be the next problem to be solved

This is a theoretical concern from epidemiological data, not a demonstrated side effect of CJC-1295, but it warrants monitoring (Renehan et al., Lancet 2004)