The New England Journal of Medicine , 387(3), 205216
Nevertheless, the combination of L-leucine, creatine, and L-Carnitine potentiated the development of muscle mass and increased strength in older adults supplemented with the L-Carnitine-combination product, likely through a common mechanism, such as promoting increase protein synthesis, increasing branched amino acid bioavailability, and decreasing protein degradation [43]
Individuals with existing kidney disease, diabetes requiring insulin, or those taking medications affecting renal function should consult their physician before starting creatine
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