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For topical formulations, concentrations of 0.1 to 0.3 percent are used, with efficacy detectable from as low as 0.01 percent

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Antioxidants 12: 1953 (2023) Hwang C, Sinskey AJ, Lodish HF

further showed that MGO in a dose-based manner impairs insulin secretion of pancreatic -cell lines MIN6 and INS-1 through increased generation of ROS and by induction of mitochondrial dysfunction (100)

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Results showed a 15% increase in mean and peak performance among the GPLC group