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Acute overdose can result in hepatic toxicity, and in some instances- fulminant hepatic failure

NizariSBasalayMChapmanPKorteNKorsakAChristieINet al

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What limits the interpretation of preclinical findings

In a nutshell, the results of this study, published online in the journal Nature Medicine , suggest that orally dosed l-carnitine is metabolized by intestinal bacteria to produce a substance called trimethylamine (TMA)

Better Therapeutic Window: The molecule's biased signaling and design aim to provide a more favorable therapeutic window, maximizing the drug's efficacy while minimizing adverse effects