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In Caco-2 monolayers, TMC with 12% quaternisation reduced transepithelial electrical resistance (TEER) in a concentration-dependent manner and significantly enhanced insulin transport at pH 4.4 (Schipper et al., 1997
(2016) 2(10):e1601273
Mechanistic investigations reveal that TB m A-Glu can be activated by GGT through cleavage of the -glutamyl bond and releasing TB m A
Similarly, intestinal organoid systems rely on ITS or B-27 as basal support alongside niche specific factors (Wnt3a, R spondin 1, Noggin) to sustain Lgr5+ stem cell compartments [7]
Unveiling the role of rhoa and ferroptosis in vascular permeability: implications for osteoarthritis
