doi: 10.1161/CIRCULATIONAHA.110.964619
Research has also demonstrated that metformin increases the abundance of Akkermansia muciniphila in the gut, which triggers the transcription of host antioxidant genes, including Nqo1 , Ho-1 , and Gpx4 [17]
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As a substrate for glutathione S-transferase (GST), this agent reacts with many of harmful chemical such as halides, epoxides and free radicals to form harmless inactive products [1]
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