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An A-base was added to the blunt ends of each strand, preparing them for ligation to the indexed adapters

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As such, glomerular lesions occur which include glomerular basement membrane thickening, podocyte effacement and loss, mesangial expansion, epithelialmesenchymal transition EMT and fibrosis, collagen deposition, damage to the capillary architecture and an influx of inflammatory cells including macrophages

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This clearly shows that in physiologically relevant concentrations SFN negatively influences the survival of malignant T-cells but not of untransformed primary human T-cells