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Data availability The authors declare that the data supporting the findings of this study are available within the Article, Source Data, and its Supplementary Information

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combination also improved several cardiometabolic parameters, including blood pressure and glucose levels, and enhanced physical functioning

The mechanisms of action inherent to these inhibitors have been thoroughly explored, drawing upon insights derived from preclinical investigations

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the median OS (030.7 years) was not reached for GLP1 RA patients, while the control group OS was 24.1 years