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In September 2025, the FDA sent thousands of warning letters and issued approximately 100 cease-and-desist letters to companies regarding their use of misleading direct-to-consumer pharmaceutical advertisements. The agency also published a green list of acceptable GLP-1 compounding ingredients intended to regulate ingredient sourcing and reduce the risk of unsafe compounded products

Diabetic Ketoacidosis and Ketosis: In individuals with T1DM, GLP-1 RAs were associated with an increased risk of ketosis, including diabetic ketoacidosis (DKA) (Class IV

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PCOS also called polyendocrine metabolic ovarian syndrome (PMOS) in recent medical literature following a 2026 global consensus rename (Teede et al